ChemicalBook CAS DataBase List Conteltinib (CT-707)

Conteltinib (CT-707) synthesis

4synthesis methods

Product Name:Conteltinib (CT-707)
CAS Number:1384860-29-0
Molecular formula:C32H45N9O3S
Molecular Weight:635.82

761440-65-7 Synthesis

1-(1-(3-Methoxy-4-nitrophenyl)piperidin-4-yl)-4-Methylpiperazine

761440-65-7
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1384860-29-0
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Yield:-

Steps:

Multi-step reaction with 4 steps
1.1: palladium 10% on activated carbon; hydrogen / methanol / 5 h / 20 °C / 3800.26 Torr
2.1: trifluoroacetic acid / 2,2,2-trifluoroethanol; 2-methoxy-ethanol / 50 h / 105 - 115 °C / Large scale
3.1: 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; caesium carbonate / toluene / 0.67 h / Inert atmosphere
3.2: 24 h / 100 - 110 °C / Inert atmosphere
4.1: trifluoroacetic acid / 80 - 100 °C

References:

Beijing Sai Lintai Pharmaceutical Co., Ltd.;Yang Limin;Zhang Chuanyu;Han Junru;Sun Deguang;Ji Chong;Zhang Xiaojun;Han Yongxin CN107200741, 2017, A

448-19-1 Synthesis

448-19-1
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$5.00/1g

1384860-29-0
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References

5H-Pyrrolo[2,3-d]pyrimidine, 2,4-dichloro-6,7-dihydro-7-[(4-methoxyphenyl)methyl]-

1312162-73-4
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1384860-29-0
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References

39929-79-8 Synthesis

39929-79-8
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$8.00/250mg

1384860-29-0
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References