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ChemicalBook CAS DataBase List (+)-CUPARENE

(+)-CUPARENE synthesis

6synthesis methods
Cyclopentanone, 3,3,4-trimethyl-4-(4-methylphenyl)-, (4S)-

125590-25-2
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(+)-CUPARENE

56324-31-3
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Yield:56324-31-3 76%

Reaction Conditions:

Stage #1: (R)-(-)-β-cuparenonewith hydrazine in ethylene glycol;diethylene glycol at 185; for 2 h;
Stage #2: with sodium in ethylene glycol;diethylene glycol; for 4 h;Heating;

References:

Aavula, Bhasker Reddy;Cui, Qi;Mash, Eugene A. [Tetrahedron Asymmetry,2000,vol. 11,# 23,p. 4681 - 4686]