ChemicalBook CAS DataBase List CYCLOHEXANONE PHENYLHYDRAZONE

CYCLOHEXANONE PHENYLHYDRAZONE synthesis

4synthesis methods

Product Name:CYCLOHEXANONE PHENYLHYDRAZONE
CAS Number:946-82-7
Molecular formula:C12H16N2
Molecular Weight:188.27

108-94-1 Synthesis

108-94-1
531 suppliers
$12.00/50g

100-63-0 Synthesis

100-63-0
359 suppliers
$10.00/1g

946-82-7
14 suppliers
$60.00/500mg

Yield:946-82-7 90%

Reaction Conditions:

with 1-deoxy-1-(methylamino)-D-glucitol in ethanol;water at 20; for 0.416667 h;Green chemistry;

Steps:

General procedure for synthesis of hydrazones

General procedure: Meglumine (0.15 mmol) was added to a mixture of carbonyl compound (1 mmol) andhydrazine (1 mmol) in water-ethanol (1:1, 4 ml). The reaction mixture was stirred at room temperature and monitored by thin-layer chromatography (TLC). After completion of the reaction, water (5 ml) and ethyl acetate (5 ml) were added and the product was extracted with ethyl acetate. The organic phase was dried over anhydrous Na2SO4, and the solvent was removed under vacuum. The crude product was then purified by column chromatography or recrystallized (petroleum ether-EtOAc).

References:

Zhang, Mo;Shang, Ze-Ren;Li, Xiao-Tang;Zhang, Jia-Nan;Wang, Yong;Li, Kang;Li, Yang-Yang;Zhang, Zhan-Hui [Synthetic Communications,2017,vol. 47,# 2,p. 178 - 187]

59-88-1 Synthesis