Cyclopentanone, 3-(2-fluorophenyl)-, (3S)- synthesis
1synthesis methods
- Product Name:Cyclopentanone, 3-(2-fluorophenyl)-, (3S)-
- CAS Number:1175638-72-8
- Molecular formula:C11H11FO
- Molecular Weight:178.2
Yield:1175638-72-8 98%
Reaction Conditions:
with chlorobis(ethylene)rhodium(I) dimer;potassium phosphate tribasic trihydrate;C19H23NOS in 1,4-dioxane;water at 20; for 3 h;Inert atmosphere;optical yield given as %ee;enantioselective reaction;
References:
Feng, Xiangqing;Wang, Yazhou;Wei, Beibei;Yang, Jing;Du, Haifeng [Organic Letters,2011,vol. 13,# 13,p. 3300 - 3303] Location in patent:supporting information; experimental part