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Cyclopropanecarboxamide, N-4-pyridinyl- (9CI) synthesis

1synthesis methods
-

Yield:186253-90-7 10%

Reaction Conditions:

with benzotriazol-1-ol;1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride;triethylamine in N,N-dimethyl-formamide at 18;

References:

Giannetti, Anthony M.;Zheng, Xiaozhang;Skelton, Nicholas J.;Wang, Weiru;Bravo, Brandon J.;Bair, Kenneth W.;Baumeister, Timm;Cheng, Eric;Crocker, Lisa;Feng, Yezhen;Gunzner-Toste, Janet;Ho, Yen-Ching;Hua, Rongbao;Liederer, Bianca M.;Liu, Yongbo;Ma, Xiaolei;O'Brien, Thomas;Oeh, Jason;Sampath, Deepak;Shen, Youming;Wang, Chengcheng;Wang, Leslie;Wu, Hongxing;Xiao, Yang;Yuen, Po-Wai;Zak, Mark;Zhao, Guiling;Zhao, Qiang;Dragovich, Peter S. [Journal of Medicinal Chemistry,2014,vol. 57,# 3,p. 770 - 792]