DEFLAZACORT synthesis
- Product Name:DEFLAZACORT
- CAS Number:13649-88-2
- Molecular formula:C23H29NO4
- Molecular Weight:383.48
![5'βH-5α-Pregnano[17,16-d]oxazol-20-one, 3β,11β-dihydroxy-2'-methyl- (8CI)](/CAS/20211123/GIF/13649-86-0.gif)
13649-86-0
0 suppliers
inquiry
13649-88-2
162 suppliers
$50.00/2g
Yield:-
Steps:
Multi-step reaction with 6 steps
1: Py
2: MeSO2Cl, SO2, collidine / dimethylformamide
3: aq. KOH / methanol / Heating
4: aq. CrO3 / acetone
5: (i) Br2, aq. HBr, AcOH, dioxane, (ii) LiBr, Li2CO3, DMF
6: (i) AcNHBr, HClO4, THF, (ii) Cr(OAc)2, nBuSH, DMSO
References:
Nathansohn,G. et al. [Steroids,1969,vol. 13,p. 383 - 397]