Desmethyl Lacosamide synthesis
- Product Name:Desmethyl Lacosamide
- CAS Number:175481-38-6
- Molecular formula:C12H16N2O3
- Molecular Weight:236.27
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Yield: 85%
Reaction Conditions:
in dichloromethane at 10 - 15;
Steps:
5 Preparation of Compound of Formula VI
The compound of example-4 (80.0 g) was dissolved in methylene chloride (640.0 ml) and cooled to 10-15° C. The acetic anhydride (46.24 gm) was added to the reaction mixture at 10-15° C. for 15-30 min and stirred for 30 min at the same temperature. The toluene (240 ml) was added and the isolated compound was filtered and dried to get title compound. Yield: 85%
References:
Davuluri, Ramamohan Rao;Batthini, Guruswamy;Mustyala, Swetha;Kallepalli, Sudheer;Neela, Praveen Kumar;Ponnaiah, Ravi US2014/323738, 2014, A1 Location in patent:Paragraph 0046
![Ethanamine, N-[(3,5-dichlorophenyl)methylene]-2,2-diethoxy-](/CAS/20210305/GIF/1000210-73-0.gif)
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175481-38-6
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175481-38-6
74 suppliers
$50.00/2 mg
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108-24-7
5 suppliers
$14.00/250ML
175481-38-6
74 suppliers
$50.00/2 mg
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108-24-7
5 suppliers
$14.00/250ML
175481-38-6
74 suppliers
$50.00/2 mg