ChemicalBook CAS DataBase List Di-tert-Butyl malonate

Di-tert-Butyl malonate synthesis

6synthesis methods

Product Name:Di-tert-Butyl malonate
CAS Number:541-16-2
Molecular formula:C11H20O4
Molecular Weight:216.27

15960-79-9
1 suppliers
inquiry

541-16-2
244 suppliers
$14.00/5g

Yield:-

Reaction Conditions:

with N-ethyl-N,N-diisopropylamine in ethanol at 20; for 4 h;Irradiation;Inert atmosphere;Reagent/catalyst;

Steps:

2.3. Photocatalytic debromination of organic bromides
General procedure: An oven-dried 10 mL glass vial was loaded with the corresponding heterogeneous Pt complex (1 mol% of Pt). Then, 1 mL of absolute ethanol, N,N-diisopropylethylamine (0.3 mmol) and the corresponding organic bromide 1 (0.1 mmol) were added to thevial. The reaction mixture was degassed by three cycles of freezepumpthaw. Next, the reaction was stirred under irradiation using a custom-made ‘‘light box” (see S.I.) at rt. After 24 h, the reaction mixture was filtered over Celite and the crude was purified by flash chromatography to afford the corresponding debrominated product 2.

References:

González-Muñoz, Daniel;Casado-Sánchez, Antonio;del Hierro, Isabel;Gómez-Ruiz, Santiago;Cabrera, Silvia;Alemán, José [Journal of Catalysis,2019,vol. 373,p. 374 - 383]

FullText

141-82-2 Synthesis