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ChemicalBook CAS DataBase List DIETHYL 4-OXOCYCLOHEXANE-1,1-DICARBOXYLATE

DIETHYL 4-OXOCYCLOHEXANE-1,1-DICARBOXYLATE synthesis

6synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: potassium tert-butylate / tetrahydrofuran / 4 h / 10 - 35 °C / Inert atmosphere
2: water; sodium chloride / dimethyl sulfoxide / 3.5 h / 160 °C / Inert atmosphere

References:

BRISTOL-MYERS SQUIBB COMPANY;UEDA, Yasutsugu;CONNOLLY, Timothy P.;JOHNSON, Barry L.;LI, Chen;NAIDU, B. Narasimhulu;PATEL, Manoj;PEESE, Kevin;SORENSON, Margaret E.;WALKER, Michael A.;BOWSHER, Michael S.;LI, Rongti WO2012/78834, 2012, A1