ChemicalBook CAS DataBase List Dihydrochelerythrine

Dihydrochelerythrine synthesis

12synthesis methods

Product Name:Dihydrochelerythrine
CAS Number:6880-91-7
Molecular formula:C21H19NO4
Molecular Weight:349.38

3895-92-9 Synthesis

3895-92-9
221 suppliers
$25.00/1mg

6880-91-7
120 suppliers
$37.00/1mg

Yield: 94%

Reaction Conditions:

with methanol;sodium tetrahydroborate at 20; for 0.5 h;Darkness;

Steps:

2.1 (1) Compound I-1: Dihydrochelerythrine
The compound chelerythrinechloride (120mg, 0.31mmols) was dissolved in 20mL methanol solution, sodium borohydride (100mg, 2.7mmols) was added,After stirring for 30 minutes at room temperature in the dark, stop the reaction and filter with suction.Wash the solid with ultrapure water and methanol, dry in vacuum,The white solid product dihydrochelerythrine (102 mg, yield: 94percent) was obtained.

References:

South China University of Technology;Tang Benzhong;Gao Meng;Ling Xia;Huang Letao CN111171039, 2020, A Location in patent:Paragraph 0072-0077

64-18-6 Synthesis