![](/CAS/GIF/22929-52-8.gif)
Dihydrofuran-3(2H)-one synthesis
- Product Name:Dihydrofuran-3(2H)-one
- CAS Number:22929-52-8
- Molecular formula:C4H6O2
- Molecular Weight:86.09
![3-Hydroxytetrahydrofuran](/CAS/GIF/453-20-3.gif)
453-20-3
278 suppliers
$9.00/1g
![Dihydrofuran-3(2H)-one](/CAS/GIF/22929-52-8.gif)
22929-52-8
250 suppliers
$5.00/250mg
Yield:22929-52-8 95%
Reaction Conditions:
with 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical;trichloroisocyanuric acid in dichloromethane at -5 - 20; for 1 h;Solvent;
Steps:
7
To a 1 L flask, 3-tetrahydrofuran (3-OH-THF, 60.6 g, 0.68 mol, 1 equ.) was charged, followed by DCM (620 mL) and TEMPO(1.08 g, 0.0069 mol, 0.01 equ.) The solution was cooled to -5 °C. To which TCCA (159.6 g, 0.68 mol, 1 equ.) was added in portions controlling the tern- perature around -5 °C to 0 °C. The resulting mixture was allowed to warm to rt and monitored by GC-MS, Reaction was finished in 1 h to give 95% yield (GC area%).
References:
WO2014/139080,2014,A1 Location in patent:Page/Page column 8; 9
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29212-66-6
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inquiry
![Dihydrofuran-3(2H)-one](/CAS/GIF/22929-52-8.gif)
22929-52-8
250 suppliers
$5.00/250mg
![Methyl 4-oxotetrahydrofuran-3-carboxylate](/CAS2/GIF/57595-23-0.gif)
57595-23-0
90 suppliers
$19.00/100mg
![Dihydrofuran-3(2H)-one](/CAS/GIF/22929-52-8.gif)
22929-52-8
250 suppliers
$5.00/250mg
![Tetrahydro-4-oxo-3-furoic acid ethyl ester](/CAS/GIF/89898-51-1.gif)
89898-51-1
64 suppliers
$30.00/100mg
![Dihydrofuran-3(2H)-one](/CAS/GIF/22929-52-8.gif)
22929-52-8
250 suppliers
$5.00/250mg
![3-Butyn-1-ol](/CAS/GIF/927-74-2.gif)
927-74-2
410 suppliers
$6.00/5g
![Dihydrofuran-3(2H)-one](/CAS/GIF/22929-52-8.gif)
22929-52-8
250 suppliers
$5.00/250mg