DIMETHYLDIANILINOTEREPHTHALIC ACID synthesis

Yield:10291-28-8 98.6%

Reaction Conditions:

Stage #1: dimethyl 2,5-dioxocyclohexane-1,4-dicarboxylate;p-toluidinewith acetic acid in ethanol at 102 - 105; for 4 h;Inert atmosphere;
Stage #2: with potassium hydroxide in ethanol at 60 - 70; for 1 h;Inert atmosphere;
Stage #3: with sodium anthraquinone-2-sulfonate;potassium hydroxide in ethanol; for 0.5 h;Inert atmosphere;

Steps:

Example 4 Example 4

The toluidine replacing example by dividing 2 aniline in the, to ethanol replacing example 2 methanol in the outer, other conditions and embodiment 2 are the same, to obtain 57.0 g purple powder (2,5-di-P-toluidine-based terephthalic acid), the purity of 98.6%, overall yield is 96.1%,

References:

CN105384652,2016,A Location in patent:Paragraph 0035; 0036; 0037; 0040; 0041