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18162-48-6872-50-4Methylene ChloridenaphthaleneTHFTitanium Dioxide

Doqualast synthesis

1synthesis methods
201230-82-2 Synthesis
carbon monoxide

201230-82-2
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11H-Pyrido[2,1-b]quinazolin-11-one, 2-bromo-

71937-21-8
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Doqualast

64019-03-0
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-

Yield:64019-03-0 48%

Reaction Conditions:

with calcium hydroxide;nickel carbonyl;water in N,N-dimethyl-formamide at 110 - 115; under 2068.6 Torr;

References:

Tilley;LeMahieu;Carson;Kierstead;Baruth;Yaremko [Journal of Medicinal Chemistry,1980,vol. 23,# 1,p. 92 - 95]

Doqualast Related Search:

2-AMINO-5-METHYLBENZAMIDE