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(E)-ethyl 3-amino-3-(4-bromophenyl)acrylate synthesis

3synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1.1: sodium hydride / toluene / 0.17 h / 20 °C
1.2: Reflux
2.1: ammonium acetate / methanol / 12 h / Reflux

References:

Baidya, Mrinmay;De Sarkar, Suman;Maiti, Debabrata;Roy, Lisa [Angewandte Chemie - International Edition,2022,vol. 61,# 5,art. no. E202111679][Angew. Chem.,2022,vol. 134,# 5]