ChemicalBook CAS DataBase List ERGONOVINE

ERGONOVINE synthesis

5synthesis methods

Product Name:ERGONOVINE
CAS Number:60-79-7
Molecular formula:C19H23N3O2
Molecular Weight:325.4

129-51-1
61 suppliers
$366.00/150mg

60-79-7
2 suppliers
$1320.00/5mg

Yield:60-79-7 96%

Reaction Conditions:

with sodium hydrogencarbonate in water;ethyl acetate at 20; for 0.5 h;

Steps:

3.1.1. Ergometrine 4 from the Corresponding Maleate 6
To a suspension of commercial ergometrine maleate (50 mg, 0.11 mmol) in ethyl acetate (10 mL),a saturated aqueous sodium bicarbonate solution (10 mL) was added. After stirring at room temperaturein the dark for 30 min, the layers were separated. The aqueous phase was extracted with ethyl acetate(2 10 mL). The collected organic phases were dried over sodium sulfate and filtered. After solventremoval under reduced pressure, a white solid was obtained (35 mg, 0.11 mmol, 96%).

References:

Ciceri, Samuele;Elahi, Shahrzad Reza;Ferraboschi, Patrizia;Grisenti, Paride;Meneghetti, Fiorella;Mori, Matteo [Molecules,2020,vol. 25,# 2,art. no. 331]

FullText

2749-11-3 Synthesis