Ethametsulfuron-methyl synthesis

Yield:-

Reaction Conditions:

in dichloromethane

Steps:

1 Methyl 2-[[(4-ethoxy-6-methylamino-1,3,5-triazin-2-yl)aminocarbonyl]aminosulfonyl]benzoate
EXAMPLE 1 Methyl 2-[[(4-ethoxy-6-methylamino-1,3,5-triazin-2-yl)aminocarbonyl]aminosulfonyl]benzoate To a suspension of 0.8 g of 4-ethoxy-6-methylamino-1,3,5-triazin-2-amine in 25 ml of methylene chloride was added 1.14 g of 2-(methoxycarbonyl)benzenesulfonyl isocyanate. Dissolution of the suspension occurred, followed by precipitation of a solid. After 1 hour at ambient temperature, the solid was collected and dried giving 0.9 g of the title compound, m.p. 204°-206° C. IR (nujol mull) C=O (1700 and 1730 cm^-1).

References:

E. I. Du Pont de Nemours and Company US4548638, 1985, A

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