ChemicalBook CAS DataBase List ETHYL 2,2-DIETHOXYPROPIONATE

ETHYL 2,2-DIETHOXYPROPIONATE synthesis

5synthesis methods

Product Name:ETHYL 2,2-DIETHOXYPROPIONATE
CAS Number:7476-20-2
Molecular formula:C9H18O4
Molecular Weight:190.24

617-35-6
528 suppliers
$5.00/10g

122-51-0 Synthesis

122-51-0
487 suppliers
$10.00/5ml

7476-20-2
34 suppliers
$60.00/100mg

109-94-4 Synthesis

109-94-4
464 suppliers
$10.00/10g

Yield: 61%

Reaction Conditions:

with toluene-4-sulfonic acid in ethanol

Steps:

3.a (a)
(a) 1st Stage-Preparation of Ethyl Pyruvate Diethyl Acetal Ethyl pyruvate (22ml, 0.19 mmol) was dissolved in ethanol (30 ml) and to this was added triethyl orthoformate (35 ml) and p-toluenesulphonic acid (0.5 g) and the mixture stirred at 60° C. for 15 minutes. The temperature was slowly increased to 80° C. and the ethyl formate produced in the reaction distilled off After removal of all the ethyl formate (5 hours) the remaining mixture was neutralised with triethanolamine (0.5 ml). Ethanol was removed in vacuo and the remaining liquor distilled under reduced pressure yielding the title compound as a clear colourless liquid (30.78 g, 61%), b.p. 80-83° C. at 15 mm Hg.

References:

Newcastle University Ventures Limited US6297250, 2001, B1

617-35-6
528 suppliers
$5.00/10g

122-51-0 Synthesis

122-51-0
487 suppliers
$10.00/5ml

7476-20-2
34 suppliers
$60.00/100mg

References

64-17-5 Synthesis