Ethyl 2-(morpholin-2-yl)acetate synthesis
- Product Name:Ethyl 2-(morpholin-2-yl)acetate
- CAS Number:503601-25-0
- Molecular formula:C8H15NO3
- Molecular Weight:173.21
73933-19-4
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$140.00/500mg
503601-25-0
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$414.00/1g
Yield:503601-25-0 93.25%
Reaction Conditions:
with palladium on activated charcoal;hydrogen in methanol at 20; under 2585.81 Torr; for 10 h;
Steps:
1 Compound 1-5: ethyl 2-(morpholin-2-yl)acetate
After dissolving 30 g (114 mmol) of ethyl 2-(4-benzylmorpholin-2-yl)acetate in methanol (300 mL), Pd/C (3 g) was added at room temperature under H2 (gas) 50 psi. , the reaction was carried out at room temperature for 10 h, and the reaction was directly filtered after completion of the reaction. The filtrate was concentrated to give ethyl 2-(morpholin-2-yl)acetate, 18.4 g, yield 93.25%.
References:
CN109796456,2019,A Location in patent:Paragraph 0032; 0033; 0040; 0041; 0042; 0043
37746-78-4
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$10.00/5g
503601-25-0
44 suppliers
$414.00/1g