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Ethyl 3-(4-Bromo-3-Fluorophenyl)Propanoate synthesis

2synthesis methods
-

Yield:1261778-92-0 87%

Reaction Conditions:

with sodium tetrahydroborate;cobalt(II) chloride in methanol;Inert atmosphere;

References:

Christiansen, Elisabeth;Hansen, Steffen V. F.;Urban, Christian;Hudson, Brian D.;Wargent, Edward T.;Grundmann, Manuel;Jenkins, Laura;Zaibi, Mohamed;Stocker, Claire J.;Ullrich, Susanne;Kostenis, Evi;Kassack, Matthias U.;Milligan, Graeme;Cawthorne, Michael A.;Ulven, Trond [ACS Medicinal Chemistry Letters,2013,vol. 4,# 5,p. 441 - 445] Location in patent:supporting information