![](/CAS/GIF/6825-71-4.gif)
ethyl 3,5-diaMino-1H-pyrazole-4-carboxylate synthesis
- Product Name:ethyl 3,5-diaMino-1H-pyrazole-4-carboxylate
- CAS Number:6825-71-4
- Molecular formula:C6H10N4O2
- Molecular Weight:170.17
![(Z)-ethyl 3-aMino-4,4,4-trichloro-2-cyanobut-2-enoate](/CAS/20150408/GIF/49765-05-1.gif)
49765-05-1
27 suppliers
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![ethyl 3,5-diaMino-1H-pyrazole-4-carboxylate](/CAS/GIF/6825-71-4.gif)
6825-71-4
69 suppliers
$15.00/100mg
Yield:6825-71-4 100%
Reaction Conditions:
with hydrazine hydrate in N,N-dimethyl-formamide at 100; for 3 h;
Steps:
1.2 3,5-Diamino-1H-pyrazole-4-carboxylic acid ethyl ester
(Z)-3-Amino-4,4,4-trichloro-2-cyanobut-2-enoic acid ethyl ester 1c (37 g, 0.1448 mmol) and hydrazine hydrate (18 g, 0.362 mol) were dissolved in 75 mL of N,N-dimethylformamide, heated to 100°C, and reacted for 3 hours. Concentrated under reduced pressure, the obtained residue was further analyzed and purified by silica gel column chromatography (eluent: system B) to obtain ethyl 3,5-diamino-1H-pyrazole-4-carboxylate 1d (24.6 g, yellow solid), yield: 100%.
References:
CN112194659,2021,A Location in patent:Paragraph 0065; 0067; 0072-0075
![(E)-ethyl 3-aMino-4,4,4-trichloro-2-isocyanobut-2-enoate](/CAS/20150408/GIF/22071-00-7.gif)
22071-00-7
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![ethyl 3,5-diaMino-1H-pyrazole-4-carboxylate](/CAS/GIF/6825-71-4.gif)
6825-71-4
69 suppliers
$15.00/100mg
![Ethyl cyanoacetate](/CAS/GIF/105-56-6.gif)
105-56-6
429 suppliers
$10.00/5ml
![ethyl 3,5-diaMino-1H-pyrazole-4-carboxylate](/CAS/GIF/6825-71-4.gif)
6825-71-4
69 suppliers
$15.00/100mg
![ETHYL 2-CYANO-2-(1,3-DIOXOLAN-2-YLIDEN)ACETATE](/CAS/GIF/121020-70-0.gif)
121020-70-0
27 suppliers
inquiry
![ethyl 3,5-diaMino-1H-pyrazole-4-carboxylate](/CAS/GIF/6825-71-4.gif)
6825-71-4
69 suppliers
$15.00/100mg