Ethyl 3-(Benzo[B]Thiophen-2-Yl)-3-Oxo-Propanoate synthesis
2synthesis methods
- Product Name:Ethyl 3-(Benzo[B]Thiophen-2-Yl)-3-Oxo-Propanoate
- CAS Number:55473-29-5
- Molecular formula:C13H12O3S
- Molecular Weight:248.3
![2-Acetylbenzo[b]thiophene](/CAS/GIF/22720-75-8.gif)
Yield:55473-29-5 49%
Reaction Conditions:
Stage #1: Diethyl carbonatewith sodium hydride in toluene; for 0.0833333 h;Inert atmosphere;Claisen Condensation;
Stage #2: 2-acetyl benzo[b]thiophene in toluene;Inert atmosphere;Reflux;Claisen Condensation;
References:
Ruengsangtongkul, Sureeporn;Chaisan, Nattawadee;Thongsornkleeb, Charnsak;Tummatorn, Jumreang;Ruchirawat, Somsak [Organic Letters,2019,vol. 21,# 8,p. 2514 - 2517] Location in patent:supporting information
![BENZO[B]THIOPHENE-2-CARBONYL CHLORIDE](/CAS/GIF/39827-11-7.gif)
