Ethyl 3-(cyclopentylamino)propanoate synthesis
- Product Name:Ethyl 3-(cyclopentylamino)propanoate
- CAS Number:928788-22-1
- Molecular formula:C10H19NO2
- Molecular Weight:185.26
1003-03-8
231 suppliers
$10.00/1g
140-88-5
544 suppliers
$12.00/100ml
928788-22-1
12 suppliers
$199.00/500mg
Yield:928788-22-1 99%
Reaction Conditions:
in ethanol; for 12 h;Cooling with ice;
Steps:
6.1 Step 1: Synthesis of intermediate ethyl 3-(cyclopentylamino)propionate
The material cyclopentylamine (5.1 g, 60 mmol, 1.0 eq.) was dissolved in ethanol (10 mL).
Then the solution was slowly added with ethyl acrylate (5.0 g, 50 mmol, 1.0 eq.) dropwise under an ice bath to react for 12 h.
After no materials were left, as detected by TLC, the reaction solution was concentrated under reduced pressure to give a product (9.2 g, yield: 99%).
References:
EP3892621,2021,A1 Location in patent:Paragraph 0241-0243
623-71-2
159 suppliers
$27.57/250mgs:
1003-03-8
231 suppliers
$10.00/1g
928788-22-1
12 suppliers
$199.00/500mg
4244-84-2
332 suppliers
$5.00/1g
120-92-3
422 suppliers
$11.00/25g
928788-22-1
12 suppliers
$199.00/500mg