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1093873-80-3

Ethyl 4-fluoro-1H-pyrrole-2-carboxylate synthesis

1synthesis methods
Ethyl 4-fluoro-1H-pyrrole-2-carboxylate

1093873-80-3
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1H-Pyrrole-2-carboxylic acid, 4,5-difluoro-, ethyl ester

1460286-60-5
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Yield:1460286-60-5 25%

Reaction Conditions:

with Selectfluor in acetonitrile at 70; for 0.0833333 h;Microwave irradiation;

References:

Buchstaller, Hans-Peter;Anlauf, Uwe;Dorsch, Dieter;K?gler, Sarah;Kuhn, Daniel;Lehmann, Martin;Leuthner, Birgitta;Lodholz, Sara;Musil, Djordje;Radtki, Daniela;Rettig, Corinna;Ritzert, Claudio;Rohdich, Felix;Schneider, Richard;Wegener, Ansgar;Weigt, Stefan;Wilkinson, Kai;Esdar, Christina [Journal of Medicinal Chemistry,2021,vol. 64,# 14,p. 10371 - 10392]