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ChemicalBook CAS DataBase List ETHYL 5-(5-BROMO-2-THIENYL)-3-ISOXAZOLECARBOXYLATE

ETHYL 5-(5-BROMO-2-THIENYL)-3-ISOXAZOLECARBOXYLATE synthesis

2synthesis methods
ethyl 4-(5-bromo-2-thienyl)-2,4-dioxobutanoate

1178492-36-8
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ETHYL 5-(5-BROMO-2-THIENYL)-3-ISOXAZOLECARBOXYLATE

423768-50-7
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Yield:423768-50-7 78%

Reaction Conditions:

with hydroxylamine hydrochloride in ethanol;Reflux;

References:

Fernández-Bachiller, María Isabel;Hwang, Songhwan;Schembri, María Elena;Lindemann, Peter;Guberman, Mónica;Herziger, Svenja;Specker, Edgar;Matter, Hans;Will, David W.;Czech, J?rg;Wagner, Michael;Bauer, Armin;Schreuder, Herman;Ritter, Kurt;Urmann, Matthias;Wehner, Volkmar;Sun, Han;Nazaré, Marc [Journal of Medicinal Chemistry,2022,vol. 65,# 19,p. 13013 - 13028] Location in patent:supporting information

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