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Ethyl 5-AMinothieno[2,3-d]pyriMidine-6-carboxylate synthesis

1synthesis methods
-

Yield:59488-80-1 48%

Reaction Conditions:

with sodium ethanolate in N,N-dimethyl-formamide at 20; for 4 h;Condensation;

References:

Meyer, Michael D.;Altenbach, Robert J.;Basha, Fatima Z.;Carroll, William A.;Condon, Stephen;Elmore, Steven W.;Kerwin Jr., James F.;Sippy, Kevin B.;Tietje, Karin;Wendt, Michael D.;Hancock, Arthur A.;Brune, Michael E.;Buckner, Steven A.;Drizin, Irene [Journal of Medicinal Chemistry,2000,vol. 43,# 8,p. 1586 - 1603]