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ChemicalBook CAS DataBase List ethyl 7-(benzyloxy)-1H-indole-2-carboxylate

ethyl 7-(benzyloxy)-1H-indole-2-carboxylate synthesis

2synthesis methods
-

Yield:84639-06-5 76%

Reaction Conditions:

Stage #1: 1-(benzyloxy)-3-methyl-2-nitrobenzene;oxalic acid diethyl esterwith potassium tert-butylate in diethyl ether; for 22 h;Reflux;
Stage #2: with iron in acetic acid at 80; for 17 h;

References:

Hirao, Shotaro;Yoshinaga, Yuki;Iwao, Masatomo;Ishibashi, Fumito [Tetrahedron Letters,2010,vol. 51,# 3,p. 533 - 536] Location in patent:scheme or table