ethyl N-ethyl-beta-alaninate synthesis
- Product Name:ethyl N-ethyl-beta-alaninate
- CAS Number:23651-62-9
- Molecular formula:C7H15NO2
- Molecular Weight:145.2
75-04-7
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23651-62-9
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Yield:23651-62-9 96.5%
Reaction Conditions:
in ethanol;water at 20; for 2.5 h;
Steps:
14.1 Step 1: Synthesis of intermediate ethyl 3-(ethylamino)propionate
65% aqueous ethylamine solution (29.1 g, 419.51 mmol, 1.4 eq., 65%) was dissolved in ethanol (100 mL).
Then the solution was added with a solution of ethyl acrylate (30.00 g, 299.65 mmol, 1.0 eq.) in ethanol (20 mL) dropwise (1.5 h).
After addition, the mixture was stirred at room temperature for 1 h. The reaction solution was concentrated to give a product (42.0 g, yield: 96.5%).
References:
EP3892621,2021,A1 Location in patent:Paragraph 0335-0337
1094629-96-5
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23651-62-9
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$158.00/500mg
539-74-2
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23651-62-9
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$158.00/500mg
109-89-7
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140-88-5
514 suppliers
$12.00/100ml
23651-62-9
15 suppliers
$158.00/500mg