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ChemicalBook CAS DataBase List FK 888

FK 888 synthesis

4synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 3 steps
1: HOBT, WSCD / CH2Cl2 / 2 h / Ambient temperature
2: 100 percent / HCl / CH2Cl2; ethyl acetate / 45 h / Ambient temperature
3: 91.9 percent / HOBT, WSCD / CH2Cl2 / Ambient temperature

References:

Hagiwara, Daijiro;Miyake, Hiroshi;Igari, Norihiro;Karino, Masako;Maeda, Yasue;et al. [Journal of Medicinal Chemistry,1994,vol. 37,# 13,p. 2090 - 2099]

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