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ChemicalBook CAS DataBase List Flurbiprofen Related Impurity 2

Flurbiprofen Related Impurity 2 synthesis

7synthesis methods
Propanedioic acid, 2-(2-fluoro[1,1'-biphenyl]-4-yl)-2-methyl-, 1,3-dimethyl ester

543688-88-6
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Yield:42771-82-4 85%

Reaction Conditions:

with potassium hydroxide in ethanol;water at 0; for 1 h;

References:

Terao, Yosuke;Ijima, Yoichiro;Kakidani, Hitoshi;Ohta, Hiromichi [Bulletin of the Chemical Society of Japan,2003,vol. 76,# 12,p. 2395 - 2397]

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