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FURAN-2-YLMETHYL-[2-(1H-INDOL-3-YL)-ETHYL]-AMINE synthesis

5synthesis methods
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Yield:77960-15-7 94%

Reaction Conditions:

Stage #1: 2-furancarboxaldehyde;tryptamine in methanol at 20; for 4 h;Inert atmosphere;
Stage #2: with methanol;sodium tetrahydridoborate at 0; for 1 h;Inert atmosphere;

References:

Milcendeau, Pierre;Gandon, Vincent;Guinchard, Xavier [Advanced Synthesis and Catalysis,2021,vol. 363,# 11,p. 2893 - 2902] Location in patent:supporting information