gambirine synthesis

Yield:29472-77-3 75%

Reaction Conditions:

with aluminum (III) chloride;ethanethiol in dichloromethane at 0 - 20; for 2 h;Inert atmosphere;

References:

León, Francisco;Obeng, Samuel;Mottinelli, Marco;Chen, Yiming;King, Tamara I.;Berthold, Erin C.;Kamble, Shyam H.;Restrepo, Luis F.;Patel, Avi;Gamez-Jimenez, Lea R.;Lopera-Londo?o, Carolina;Hiranita, Takato;Sharma, Abhisheak;Hampson, Aidan J.;Canal, Clinton E.;McMahon, Lance R.;McCurdy, Christopher R. [Journal of Medicinal Chemistry,2021,vol. 64,# 18,p. 13510 - 13523]