Gc-6506-wettable powder granules synthesis

Yield:-

Reaction Conditions:

with phosphorous acid trimethyl ester in Dimethyldisulphide

Steps:

III Preparation of O,O-Dimethyl-O-(p-methylthiophenyl) Phosphate
EXAMPLE III Preparation of O,O-Dimethyl-O-(p-methylthiophenyl) Phosphate p-Mercaptophenol (12.6g, 0.10 mole) was dissolved in 20g (0.21 mole) of dimethyl disulfide. Then 24.8g (0.20 mole) of trimethyl phosphite was added dropwise so as to control the exothermic reaction at or below 45° C. The solution was then warmed to 50° C for 1 hour. After cooling to room temperature the solution was distilled to afford 15.1g (69% yield) of product (b.p. 138°-140° C at 0.1 mm). The product was identical to that obtained in the conventional manner.⁵

References:

Mobil Oil Corporation US4003966, 1977, A

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