GNF 5837 synthesis
- Product Name:GNF 5837
- CAS Number:1033769-28-6
- Molecular formula:C28H21F4N5O2
- Molecular Weight:535.49
364-73-8
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1033769-28-6
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$24.00/1mg
Yield:-
Steps:
Multi-step reaction with 7 steps
1.1: sodium hydride / dimethyl sulfoxide; mineral oil / 20 - 60 °C
1.2: 14 h / 60 °C
2.1: hydrogenchloride / water; acetic acid / 110 °C
3.1: sulfuric acid / 80 °C
4.1: palladium diacetate; caesium carbonate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene / 1,4-dioxane / 110 °C
5.1: palladium 10% on activated carbon; hydrogen / acetic acid / 20 °C
6.1: triethylamine / tetrahydrofuran / 20 °C
7.1: piperidine / ethanol / 2 h / 80 °C
References:
Albaugh, Pam;Fan, Yi;Mi, Yuan;Sun, Fangxian;Adrian, Francisco;Li, Nanxin;Jia, Yong;Sarkisova, Yelena;Kreusch, Andreas;Hood, Tami;Lu, Min;Liu, Guoxun;Huang, Shenlin;Liu, Zuosheng;Loren, Jon;Tuntland, Tove;Karanewsky, Donald S.;Seidel, H. Martin;Molteni, Valentina [ACS Medicinal Chemistry Letters,2012,vol. 3,# 2,p. 140 - 145]
1003-29-8
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$10.00/1g
![Ethanamine, N-[(3,5-dichlorophenyl)methylene]-2,2-diethoxy-](/CAS/20210305/GIF/1000210-73-0.gif)
1000210-73-0
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1033769-28-6
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199328-35-3
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1033769-28-6
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6127-11-3
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$17.00/250mg
1033769-28-6
112 suppliers
$24.00/1mg