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ChemicalBook CAS DataBase List Gonadorelin

Gonadorelin synthesis

1synthesis methods
51776-33-1 Synthesis
H-SER-TYR-GLY-LEU-ARG-PRO-GLY-NH2

51776-33-1
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L-Tryptophan, N-[N-(5-oxo-L-prolyl)-L-histidyl]-, ethyl ester (9CI)

105823-83-4
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Yield:33515-09-2 71%

Reaction Conditions:

with potassium hydroxide;potassium chloride;α-chymotrypsin in dimethyl sulfoxide at -15; for 1 h;Product distribution;other time, temperature;

References:

Schuster;Aaviksaar;Jakubke [Tetrahedron Letters,1992,vol. 33,# 20,p. 2799 - 2802]

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