H-3,5-DIIODO-TYR-OME HCL synthesis
1synthesis methods
- Product Name:H-3,5-DIIODO-TYR-OME HCL
- CAS Number:151266-48-7
- Molecular formula:C10H12ClI2NO3
- Molecular Weight:483.47
Yield:151266-48-7 98%
Reaction Conditions:
Stage #1: methanolwith thionyl chloride at 0; for 0.166667 h;Inert atmosphere;
Stage #2: 3,5-diiodo-l-tyrosine at 20; for 16 h;
References:
Rajput, Sunnia;McLean, Kirsty J.;Poddar, Harshwardhan;Selvam, Irwin R.;Nagalingam, Gayathri;Triccas, James A.;Levy, Colin W.;Munro, Andrew W.;Hutton, Craig A. [Journal of Medicinal Chemistry,2019,vol. 62,# 21,p. 9792 - 9805] Location in patent:supporting information