ChemicalBook CAS DataBase List H-GLU(ANILIDE)-OH

H-GLU(ANILIDE)-OH synthesis

9synthesis methods

Product Name:H-GLU(ANILIDE)-OH
CAS Number:5963-60-0
Molecular formula:C11H14N2O3
Molecular Weight:222.24

56-86-0 Synthesis

56-86-0
792 suppliers
$5.00/25g

5963-60-0
27 suppliers
$45.00/25mg

Yield:-

Steps:

Multi-step reaction with 6 steps
1: 98 percent / triethylamine / methanol / 3 h
2: 90 percent / toluenesulfonic acid / toluene / 3 h / Heating
3: thionyl chloride / CH₂Cl₂ / 0.5 h / Heating
4: pyridine / CH₂Cl₂ / 0.25 h / 20 °C
5: lithium hydroxide / tetrahydrofuran; H₂O / 0.5 h / 5 °C
6: hydrogen / Pd/C / methanol

References:

Esslinger, C. Sean;Cybulski, Kimberly A.;Rhoderick, Joseph F. [Bioorganic and Medicinal Chemistry,2005,vol. 13,# 4,p. 1111 - 1118]