ChemicalBook CAS DataBase List 1,2,4,5-Cyclohexanetetracarboxylic Dianhydride

1,2,4,5-Cyclohexanetetracarboxylic Dianhydride synthesis

8synthesis methods

Product Name:1,2,4,5-Cyclohexanetetracarboxylic Dianhydride
CAS Number:2754-41-8
Molecular formula:C10H8O6
Molecular Weight:224.17

In a 100 mL three-necked flask equipped with a thermometer, a magnetic stirrer, a water separator, and a condenser tube was added 9.64 g of hydrogenatedEthylbenzene tetracarboxylate, 1mL of concentrated sulfuric acid, 5mL of acetic acid and 50mL of xylene were heated to 130°C. During the reaction, the reaction temperature was maintained at reflux, and the reaction continuously removed water for 5 hours. , cooling down to room temperature, suction filtration, filter cake washed with acetone, dried at room temperature under reduced pressure to give white solid 1,2,4,5-cyclohexane tetracarboxylic acid anhydride 4.80g, yield: 82.8%.

CYCLOHEXANE-1 2 4 5-TETRACARBOXYLIC ACI&

15383-49-0
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$6.00/250mg

1,2,4,5-Cyclohexanetetracarboxylic Dianhydride

2754-41-8
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$5.00/1g

Yield:2754-41-8 97.5%

Reaction Conditions:

with acetic anhydride for 1 h;Inert atmosphere;Reflux;

Steps:

2
39.2 g of hydrogenated pyromellitic acid (0.15 mol) having a purity of 99.50% obtained in the step 1 was added to 500 mL four-necked flask , meanwhile adding 120 g of acetic anhydride (1.18 mol) and heating to reflux under a nitrogen atmosphere ,to carry out Dehydration reaction for 1h. [0026] After the reaction was completed, the solution was cooled to precipitate white crystals and filtered. The filter cake was dried under reduced pressure to obtain 32.5 g of white solid hydrogenated pyromellitic dianhydride. The yield was 97.5% and the purity of GC was 99.85%.

References:

Changzhou Sunshine Pharmaceutical Co., Ltd.;Hu Guoyi;Wu Jianhua;Min Xuefeng;Zhou Guoping CN103992330, 2016, B Location in patent:Paragraph 5-7

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