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1206970-18-4

Imidazo[1,2-a]pyridine, 3-(6-chloro-2-pyrazinyl)- synthesis

3synthesis methods
-

Yield:1206970-18-4 62%

Reaction Conditions:

Stage #1: 2-chloro-6-[(Z)-2-ethoxyethenyl]pyrazinewith N-Bromosuccinimide in 1,4-dioxane at 20; for 0.166667 h;
Stage #2: 2-aminopyridine in 1,4-dioxane at 100; for 0.166667 h;Microwave irradiation;

References:

Collins, Michael Raymond;Huang, Qinhua;Ornelas, Martha A.;Scales, Stephanie A. [Tetrahedron Letters,2010,vol. 51,# 27,p. 3528 - 3530] Location in patent:experimental part