Imidazolidine, 2,2-dichloro-1,3-dimethyl- synthesis

Yield:343927-22-0 85%

Reaction Conditions:

with trichlorophosphate in toluene at 23 - 40; for 5 h;

Steps:

Preparation of the Compound of the Formula (III-1) (CNC Catalyst); (N,N-Dimethylimidazolidino)tetramethylguanidinium chloride 600 ml of toluene were initially charged and 360 g of phosgene were added at room temperature (23° C.) within 3.5 h. Subsequently, 344 g (3.00 mol) of 1,3-dimethylimidazolidinone in 450 ml of toluene were added within 1.5 h, in the course of which the temperature was kept at 40° C. After the gas evolution had ended, excess phosgene was removed by bubbling it out with nitrogen. The suspension is filtered under inert gas and 438 g (2.56 mol) of (N,N-dimethylimidazolidino) chloride were obtained as a colourless solid. Yield: 85%. m.p.: 156-158° C.

References:

US2006/9643,2006,A1 Location in patent:Page/Page column 4