![](/CAS/GIF/63610-08-2.gif)
Indobufen synthesis
- Product Name:Indobufen
- CAS Number:63610-08-2
- Molecular formula:C18H17NO3
- Molecular Weight:295.34
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![Indobufen](/CAS/GIF/63610-08-2.gif)
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Yield:-
Reaction Conditions:
with hydrogenchloride in water;
Steps:
1-3 preparation of indobufen
EIPA (295.33 mg, 1 mmol) is dissolved in 15 mL of THF (solution A). Ethyl bromide (149.48 , 2 mmol) is dissolved in 15 mL of THF (solution B). A and B solutions are pumped, respectively, mixed at the T-junction maintained at -10 ° C and passed through a column reactor filled with K 2 CO 3 at 100 ° C. After separating and purifying EIPB from the reaction mixture, it is added to distilled water and hydrolyzed by adding HCl to obtain indobufen.
References:
KR101778331,2017,B1 Location in patent:Paragraph 0034; 0070; 0071
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![Indobufen](/CAS/GIF/63610-08-2.gif)
63610-08-2
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