ChemicalBook CAS DataBase List L-A-PHOSPHATIDIC ACID, DIPALMITOYL*FREE ACID

L-A-PHOSPHATIDIC ACID, DIPALMITOYL*FREE ACID synthesis

6synthesis methods

Product Name:L-A-PHOSPHATIDIC ACID, DIPALMITOYL*FREE ACID
CAS Number:7091-44-3
Molecular formula:C35H69O8P
Molecular Weight:648.89

Hexadecanoic acid, 1-[[(dichlorophosphinyl)oxy]methyl]-1,2-ethanediyl ester, (R)- (9CI)

71321-85-2
0 suppliers
inquiry

L-A-PHOSPHATIDIC ACID, DIPALMITOYL*FREE ACID

7091-44-3
13 suppliers
inquiry

Yield:7091-44-3 89.68%

Reaction Conditions:

with water;sodium carbonate for 12 h;Reagent/catalyst;

Steps:

1.2; 1.3; 4-5

_{(2) Add 1200ml saturated sodium carbonate aqueous solution dropwise to the reaction solution, stir and hydrolyze for 12 hours, A large amount of solids are produced, filtered, and the filter cake is vacuum dried for 24 hours. The crude dipalmitoyl phosphatidic acid was obtained. (3) Dissolve the crude dipalmitoyl phosphatidic acid in 2300 ml of a mixed solution of methanol and chloroform (methanol: chloroform=1:6), Heat to 40°C, stir to dissolve for 1 hour, filter while hot, The filtrate was slowly cooled to 0°C to crystallize for 12 hours, filtered, The filter cake was vacuum dried at room temperature for 24 hours to obtain dipalmitoyl phosphatidic acid.}

References:

CN111253434,2020,A Location in patent:Paragraph 0029; 0031-0035; 0045-0058

30334-71-5 Synthesis