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L-ISOLEUCINE-2-D1 synthesis

1synthesis methods
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Yield:127290-60-2 84%

Reaction Conditions:

with pyridoxal 5'-phosphate;water-d2;sodium salt of phosphorous acid at 37; pH=8.4; for 16 h;Kinetics;Enzymatic reaction;regioselective reaction;Temperature;

References:

Doyon, Tyler J.;Buller, Andrew R. [Journal of the American Chemical Society,2022,vol. 144,# 16,p. 7327 - 7336] Location in patent:supporting information