ChemicalBook CAS DataBase List Lipstatin

Lipstatin synthesis

6synthesis methods

Product Name:Lipstatin
CAS Number:96829-59-3
Molecular formula:C29H49NO5
Molecular Weight:491.7

66-25-1
313 suppliers
$16.80/100G

96829-59-3
107 suppliers
inquiry

Yield:-

Steps:

Multi-step reaction with 11 steps
1: 100 percent / NaN(SiMe₃)2 / tetrahydrofuran / 12 h / -100 deg C to RT
2: p-TsOH / H₂O; tetrahydrofuran / 0.17 h / Heating
3: LiAlH₄ / tetrahydrofuran / 2.5 h / -90 to -20 deg C
4: 90 percent / PPh₃Br₂, pyridine / acetonitrile / 1 h / -7 to RT
5: 100 percent / acetonitrile / 48 h / Heating
6: 86 percent / NaN(SiMe₃)2 / tetrahydrofuran / 12 h / -100 deg C to RT
7: 93 percent / DIBAH / CH₂Cl₂ / 1 h / -90 °C
8: 81 percent / EtAlCl₂ / diethyl ether; hexane / 2.5 h / -40 to -20 deg C
9: 77 percent / 40percent aq. HF / acetonitrile / 12 h / 0 deg C to RT
10: 70 percent / Bu₄NF / tetrahydrofuran / 0.25 h / -90 °C
11: 50 percent / PPh₃, diethyl azodicarboxylate / tetrahydrofuran / 1.5 h / 0 deg C to RT