![](/CAS/GIF/82034-46-6.gif)
Loteprednol etabonate synthesis
- Product Name:Loteprednol etabonate
- CAS Number:82034-46-6
- Molecular formula:C24H31ClO7
- Molecular Weight:466.95
![Prednisolone](/CAS/GIF/50-24-8.gif)
50-24-8
584 suppliers
$14.10/100mg
![Loteprednol etabonate](/CAS/GIF/82034-46-6.gif)
82034-46-6
327 suppliers
$28.00/5mg
Yield:-
Steps:
Multi-step reaction with 3 steps
1.1: sodium periodate / methanol; water / 0.5 h / Heating; Large scale
2.1: triethylamine / dichloromethane / 0.5 h / 0 - 10 °C / Large scale
3.1: sodium ethanolate / N,N,N,N,N,N-hexamethylphosphoric triamide / 24 h / 20 °C / Large scale
3.2: 2 h / 20 °C / Large scale
References:
Shanghai Qingsong Pharmaceutical Co., Ltd.;Zhang, Jian;Chen, Xiaona;Gao, Junfeng;Zhang, Shubin;Tan, Zhouhong CN106554383, 2017, A
![(11beta,17alpha)-11,17-dihydroxy-3-oxoandrosta-1,4-diene-17-carboxylic acid](/CAS/GIF/37927-29-0.gif)
37927-29-0
41 suppliers
inquiry
![Loteprednol etabonate](/CAS/GIF/82034-46-6.gif)
82034-46-6
327 suppliers
$28.00/5mg