ChemicalBook CAS DataBase List LY-2795050

LY-2795050 synthesis

10synthesis methods

Product Name:LY-2795050
CAS Number:1346133-08-1
Molecular formula:C23H22ClN3O2
Molecular Weight:407.89

123-08-0 Synthesis

123-08-0
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1346133-08-1
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Yield:-

Steps:

Multi-step reaction with 3 steps
1: potassium carbonate / N,N-dimethyl-formamide / 2 h / Heating
2: dihydrogen peroxide / water; dimethyl sulfoxide / 2 h / 10 - 20 °C / Alkaline conditions
3: sodium tris(acetoxy)borohydride; acetic acid / 1,2-dichloro-ethane / 20 °C

References:

Mitch, Charles H.;Quimby, Steven J.;Diaz, Nuria;Pedregal, Concepcion;De La Torre, Marta G.;Jimenez, Alma;Shi, Qing;Canada, Emily J.;Kahl, Steven D.;Statnick, Michael A.;McKinzie, David L.;Benesh, Dana R.;Rash, Karen S.;Barth, Vanessa N. [Journal of Medicinal Chemistry,2011,vol. 54,# 23,p. 8000 - 8012]