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ChemicalBook CAS DataBase List m-PEG7-CH2COOH

m-PEG7-CH2COOH synthesis

2synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1.1: sodium hydride / tetrahydrofuran / 0.25 h / 0 - 20 °C
1.2: 4 h / 20 °C
2.1: hydrogenchloride / dichloromethane / 3 h / 20 °C

References:

Ardelyx, Inc.;Lewis, Jason G.;Jacobs, Jeffrey W.;Reich, Nicholas;Leadbetter, Michael R.;Bell, Noah;Chang, Han-Ting;Chen, Tao;Navre, Marc;Charmot, Dominique;Carreras, Christopher;Labonte, Eric US9301951, 2016, B2

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