ChemicalBook CAS DataBase List (+)-Medicarpin

(+)-Medicarpin synthesis

8synthesis methods

Product Name:(+)-Medicarpin
CAS Number:33983-39-0
Molecular formula:C16H14O4
Molecular Weight:270.28

6496-89-5 Synthesis

6496-89-5
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32383-76-9
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33983-39-0
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Yield:-

Steps:

Multi-step reaction with 4 steps
1.1: boron trifluoride diethyl etherate / 2 h / 90 - 100 °C
1.2: 50 - 90 °C
2.1: aluminum (III) chloride / acetonitrile / 0 °C / Reflux
2.2: Cooling with ice
3.1: sodium tetrahydroborate / ethanol / 0 - 20 °C
4.1: Lux cellulose-1 PHENOMENIX column / acetonitrile; water / Resolution of racemate

References:

Goel, Atul;Kumar, Amit;Hemberger, Yasmin;Raghuvanshi, Ashutosh;Jeet, Ram;Tiwari, Govind;Knauer, Michael;Kureel, Jyoti;Singh, Anuj K.;Gautam, Abnish;Trivedi, Ritu;Singh, Divya;Bringmann, Gerhard [Organic and Biomolecular Chemistry,2012,vol. 10,# 48,p. 9583 - 9592]