![](/CAS/GIF/573-20-6.gif)
Menadiol diacetate synthesis
- Product Name:Menadiol diacetate
- CAS Number:573-20-6
- Molecular formula:C15H14O4
- Molecular Weight:258.27
![VITAMIN K4](/CAS/GIF/481-85-6.gif)
481-85-6
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$35.00/100mg
![Acetic anhydride](/CAS/20180808/GIF/108-24-7.gif)
108-24-7
5 suppliers
$14.00/250ML
![Menadiol diacetate](/CAS/GIF/573-20-6.gif)
573-20-6
229 suppliers
$25.00/10g
Yield:573-20-6 90.2 %
Reaction Conditions:
with pyridine at 65 - 70;
Steps:
1.2; 2; 3.2
(2) the above0.45 g (0.006 mol) of pyridine is added to the 2-methyl-1,4-naphthalenediol ethyl acetate solution,17.1 g (0.167 mol) of acetic anhydride was added dropwise at 65-70° C. and aged at the same temperature for 3 hours. The organic layer was washed with city water and 5% sodium bicarbonate water,The organic layer was concentrated, and a mixed solution of isopropanol (IPA) and city water was added to the residue. The resulting slurry was filtered and dried under reduced pressure to give 12.0 g of colorless crystalline powder of 1,4-diacetoxy-2-methylnaphthalene.(0.046 mol) was obtained.HPLC purity is 99.96 Area%,The yield from bisulfite trihydrate of 2-methylnaphthoquinone was 90.2%.
References:
JP2023/16443,2023,A Location in patent:Paragraph 0023-0025
![Menadione](/CAS/GIF/58-27-5.gif)
58-27-5
529 suppliers
$5.00/250mg
![Acetic anhydride](/CAS/20180808/GIF/108-24-7.gif)
108-24-7
5 suppliers
$14.00/250ML
![Menadiol diacetate](/CAS/GIF/573-20-6.gif)
573-20-6
229 suppliers
$25.00/10g
![Menadione](/CAS/GIF/58-27-5.gif)
58-27-5
529 suppliers
$5.00/250mg
![Acetic acid](/CAS/GIF/64-19-7.gif)
64-19-7
1537 suppliers
$10.00/25ML
![Menadiol diacetate](/CAS/GIF/573-20-6.gif)
573-20-6
229 suppliers
$25.00/10g
![Methanol](/CAS/GIF/67-56-1.gif)
67-56-1
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$9.00/25ml
![Menadione](/CAS/GIF/58-27-5.gif)
58-27-5
529 suppliers
$5.00/250mg
![Acetic anhydride](/CAS/20180808/GIF/108-24-7.gif)
108-24-7
5 suppliers
$14.00/250ML
![Menadiol diacetate](/CAS/GIF/573-20-6.gif)
573-20-6
229 suppliers
$25.00/10g
![1-Naphthalenol, 4-methoxy-2-methyl-, 1-acetate](/CAS/20210305/GIF/3526-72-5.gif)
3526-72-5
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inquiry
![Menadione](/CAS/GIF/58-27-5.gif)
58-27-5
529 suppliers
$5.00/250mg
![Menadiol diacetate](/CAS/GIF/573-20-6.gif)
573-20-6
229 suppliers
$25.00/10g