ChemicalBook CAS DataBase List Methoxymethyl propionate

Methoxymethyl propionate synthesis

6synthesis methods

Product Name:Methoxymethyl propionate
CAS Number:70767-92-9
Molecular formula:C5H10O3
Molecular Weight:118.13

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Yield:-

Reaction Conditions:

with potassium carbonate in propionic acid anhydride;

Steps:

7.A 7A.

7A. Preparation of Methoxymethyl propionate To 710 ml of dimethoxymethane in a 3-liter 3-neck round bottom flask was added 14.0 g of Amberlyst 15. The mixture was heated to reflux and 950 ml of propionic anhydride was added as rapidly as possible (exothermic reaction) while the flask was cooled in an ice bath. The reaction temperature was allowed to rise to 50-55° C. The mixture was stirred for 5 minutes after the addition was complete and was then filtered directly onto 14.0 g of anhydrous potassium carbonate. The filtrate was fractionally distilled through an efficient column to separate residual dimethoxymethane, methyl propionate and the product (methoxymethyl propionate). Yield: 720.7 g (fraction 4); 83.6%; >99.5% pure.

References:

US6040446,2000,A