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Methyl 2-(2-Chloro-N-methylacetamido)benzoate synthesis

1synthesis methods
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Yield:1140-19-8 68%

Reaction Conditions:

with sodium hydrogencarbonate in tetrahydrofuran;water at 0; for 2 h;Inert atmosphere;

References:

Van Kalkeren, Henri A.;Te Grotenhuis, Colet;Haasjes, Frank S.;Hommersom;Rutjes, Floris P. J. T.;Van Delft, Floris L. [European Journal of Organic Chemistry,2013,# 31,p. 7059 - 7066] Location in patent:supporting information